| Polls Gap | 1563 m | | Balsam |
| Luftee Gap | 1556 m | | Central Great Smoky Mountains |
| Beech Gap | 1545 m | | Balsam |
| Mineral Gap | 1544 m | | Western Great Smoky Mountains |
| Double Gap | 1542 m | | Balsam |
| Newfound Gap | 1539 m | | Newfound Mountain Region |
| Newfound Gap | 1539 m | | Central Great Smoky Mountains |
| Flat Top Gap | 1537 m | | Central Great Smoky Mountains |
| Snowbird Gap | 1518 m | | Nantahala Mountains |
| Bradley Gap | 1516 m | | Roan-Unaka Mountains |
| Mule Gap | 1515 m | | Central Great Smoky Mountains |
| Edmands Col | 1506 m | | Northern Peaks |
| Haw Gap | 1500 m | | Western Great Smoky Mountains |
| Sharptop Gap | 1494 m | | Eastern Great Smoky Mountains |
| Deep Gap | 1489 m | | Great Balsam Mountains |
| Brushy Gap | 1486 m | | Balsam |
| Meadow Gap | 1484 m | | Western Great Smoky Mountains |
| Buckeye Gap | 1473 m | | Central Great Smoky Mountains |
| Water Oak Gap | 1447 m | | Central Great Smoky Mountains |
| Sams Gap | 1446 m | | Central Great Smoky Mountains |